Sociomicrobiology and Pathogenic Bacteria

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چکیده

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Sociomicrobiology and Pathogenic Bacteria.

The study of microbial pathogenesis has been primarily a reductionist science since Koch's principles. Reductionist approaches are essential to identify the causal agents of infectious disease, their molecular mechanisms of action, and potential drug targets, and much of medicine's success in the treatment of infectious disease stems from that approach. But many bacteria-caused diseases cannot ...

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Long before bacteria infected humans, they infected amoebas, which remain a potentially important reservoir for human disease. Diverse soil amoebas including Dictyostelium and Acanthamoeba can host intracellular bacteria. Though the internal environment of free-living amoebas is similar in many ways to that of mammalian macrophages, they differ in a number of important ways, including temperatu...

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ژورنال

عنوان ژورنال: Microbiology Spectrum

سال: 2016

ISSN: 2165-0497

DOI: 10.1128/microbiolspec.vmbf-0019-2015